our publications
about cancer
Engineered swine models of cancer
Published in Frontiers in Genetics
Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1
Published in Nature’s Communication Biology
A new tool for mapping breast cancer risk in the tumor microenvironment
Published in Cancer Research
about cardiovascular disease
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs
Published in Nature Medicine
Peripheral vascular atherosclerosis in a novel PCSK9 gain-of-function mutant Ossabaw miniature pig model
Published in Translational Research
about orphan disease
TALEN-based gene correction for epidermolysis bullosa
Published in Molecular Therapy
About Gene Editing and Advanced Reproduction of Pigs
In vivo genome editing using a high-efficiency TALEN system
Published in Nature
Precision editing of large animal genomes
Published in Advances in Genetics
Efficient TALEN-mediated gene knockout in livestock
Published in Proceedings of the National Academy of Sciences
Precise genome editing of PDX1 by direct injection of transcription activator-like effector nucleases (TALENS) into Parthenogenetic Pig Embryos
Published in Reproduction, Fertility and Development
Efficient Nonmeiotic Allele Introgression in Livestock Using Custom Endonucleases
Published in Proceedings of National of the National Academy of Sciences
Editing Livestock Genomes with Site-Specific Nucleases
Published in the Journal of Reproduction, Fertility and Development
Live pigs produced from genome edited zygotes
Published in Scientific Reports
TALEN-mediated gene targeting in porcine spermatogonia
Published in Molecular Reproduction and Development
About Avoidance of nih-related Financial Conflicts Of Interest
media attention
Our work has been featured in the following national, international and industry media outlets:
















